> ## Documentation Index
> Fetch the complete documentation index at: https://kalarislabs.com/llms.txt
> Use this file to discover all available pages before exploring further.

# depmap — AI agent skill for scientific databases

> Query the Cancer Dependency Map (DepMap) for cancer cell line gene dependency scores (CRISPR Chronos), drug sensitivity data, and gene effect profiles.

# `depmap`

> Query the Cancer Dependency Map (DepMap) for cancer cell line gene dependency scores (CRISPR Chronos), drug sensitivity data, and gene effect profiles. Use for identifying cancer-specific vulnerabilities, synthetic lethal interactions, and validating oncology drug targets.

**Category:** [scientific-databases](/skills#scientific-databases) · **License:** CC-BY-4.0 · **Version:** 1.0

## Install

```bash theme={null}
npx research-agent-skills install depmap
npx skills add KalarisLabs/research-agent-skills --skill depmap
```

## When to use it

Query the Cancer Dependency Map (DepMap) for cancer cell line gene dependency scores (CRISPR Chronos), drug sensitivity data, and gene effect profiles. Use for identifying cancer-specific vulnerabilities, synthetic lethal interactions, and validating oncology drug targets.

## Full playbook

Read [SKILL.md](https://github.com/KalarisLabs/research-agent-skills/blob/main/skills/depmap/SKILL.md) for the complete workflow, references and any scripts. The agent installer copies the full skill folder.