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cellxgene-census

Category: scientific-databases · License: MIT · Version: 1.3 Tags: single-cell, transcriptomics, public datasets, spatial transcriptomics, bioinformatics

When to use it

Query the CZ CELLxGENE Census programmatically for versioned public single-cell and spatial transcriptomics data. Use when you need population-scale cell metadata, gene expression slices, Census summary counts, source H5AD URIs/downloads, embeddings, spatial Census data, or reference atlas comparisons across organisms, tissues, diseases, assays, and cell types. For analyzing your own local single-cell data use scanpy, anndata, or scvi-tools.

Example requests

Ask your agent in plain language, for example:
  • “How many primary human B cells are in the latest Census LTS release, broken down by tissue?”
  • “I’m writing a methods section for a lung fibrosis paper. I need all primary Homo sapiens cells from lung with disease ‘pulmonary fibrosis’ from CELLxGENE, only the columns cell_type, donor_id, dataset_id and assay, plus expression for SFTPC and KRT5, loaded into an AnnData I can pass to scanpy. My laptop has 16 GB RAM and my first attempt with get_anndata crashed with a memory error.”
  • “I want to train a cell type classifier on millions of public human brain single-cell profiles without downloading every dataset by hand. What’s the right way to stream that data into PyTorch and keep the training set reproducible?”

Install

In Claude Code you can also add the marketplace with /plugin marketplace add KalarisLabs/research-agent-skills and install the whole scientific-databases category with /plugin install scientific-databases@research-agent-skills.

Full playbook

Read SKILL.md for the complete workflow, references and any scripts. The agent installer copies the full skill folder.
Last modified on October 19, 2026