statistical-power
Category: ideation-and-design · License: MIT · Version: 1.1 · Includes scripts
Tags: power analysis, sample size, study design, statistics
When to use it
Sample-size and statistical power calculations for planning studies. Use whenever someone asks “how many subjects/samples/replicates do I need”, wants an a priori power analysis, a minimum detectable effect (MDE), a power curve, or needs to justify a sample size for a grant, IRB protocol, or pre-registration. Covers closed-form power for t-tests, ANOVA, proportions, correlations, chi-square, and regression, plus simulation-based (Monte Carlo) power for designs with no formula — logistic/Poisson regression, mixed models, cluster-randomized trials, survival, and interactions. Use this skill even when the request only mentions an effect size, alpha, or “80% power” without saying “power analysis” explicitly. For laying out the study (randomization, blocking, factorial/DOE, crossover, sequential designs) use experimental-design; for analyzing data already collected and reporting it use statistical-analysis.Example requests
Ask your agent in plain language, for example:- “how many mice per group for d=0.8, 90% power?”
- “I’m writing an R01 aim where we randomize 24 clinics (about 30 patients each) to a new intake protocol vs usual care, and the outcome is 6-month remission (binary, baseline around 35%). Our ICC from a pilot is 0.05. I need a sample size justification paragraph for the grant. Can you work out how many clinics we need to see a 10 percentage point improvement and tell me if 24 is enough?”
- “We only have budget for 12 animals per arm in our two-arm tail-suspension study, with SD around 25 seconds immobility. Before I commit to this, what’s the smallest difference between groups we could realistically pick up, and can you show how that changes if a couple of animals die?”
Install
/plugin marketplace add KalarisLabs/research-agent-skills and install the whole ideation-and-design category with /plugin install ideation-and-design@research-agent-skills.